Preoperative Flavanols Supplementation in Elderly Patients to Reduce Inflammatory Markers and Improve Mitochondrial Function

Led by Dr. Byron Fergerson, Clinical Professor and Vice Chair of Anesthesiology at UCSD Health, this study evaluates a flavanol-based supplement aimed at supporting recovery and overall health in patients 50 years or older preparing for hip or knee replacement surgery.

Study Activities

Participants will complete two in-home blood draws, take one 500 mg capsule daily for 14 days, log their intake, and answer questionnaires.

Participant Benefits

While direct health benefits cannot be guaranteed, the flavanol supplement may reduce inflammation and support antioxidant activity. Other possible benefits include improved cognition, mood, and recovery. Participants may receive up to $100 upon completion.

Eligibility Criteria
  • Age 50 or older
  • Reside in San Diego County
  • Scheduled for hip or knee replacement surgery
Additional Information

Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Principal Investigator(s)
Study Duration
2 weeks
Study Compensation
Up to $100
Email
krupp-wellness@health.ucsd.edu
Phone Number
619‑929‑0828

Weight Management: Dissemination and Implementation of Shared Medical Appointments at UC San Diego Health

The UCSD Supervised Lifestyle and Integrative Medicine (SLIM) Program for the treatment of obesity is a virtual SMA program that has a curriculum based on USPSTF recommendations for intensive lifestyle change and meets the requirements of ITLC outlined in the American College of Lifestyle Medicine position statement on ITLC.

It is run by the UC San Diego Center for Integrative Medicine, and in-person assessment visits take place at the UC San Diego Center for Weight Management. The program consists of 12 visits, covering all six pillars of Lifestyle Medicine. There are 2 pre-intervention visits for initial assessments and tailored recommendations and 2 follow-up assessments.

Study Activities

Participation includes 12 virtual group appointments, 2 pre-intervention visits, and 2 post-intervention assessments, focused on lifestyle education and personalized weight management support.

Participant Benefits

Education and tools for long-term weight management through evidence-based lifestyle interventions and support from an integrative health team.

Additional Information

Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Study Duration
6 months
Email
krupp-wellness@health.ucsd.edu
Phone Number
858‑413‑7728

Ophthalmology and Diet – Shiley Eye Institute

Glaucoma affects about 80 million people worldwide and is the leading cause of blindness. While there’s no cure, emerging evidence suggests dietary changes—specifically using “food as medicine”—may influence intraocular pressure and systemic health. Shiley Eye Institute and the KCIR are conducting a study examining eye health under a whole‑foods, plant‑based (WFPB) diet.

Study Activities
  • Learning healthy cooking basics and trying therapeutic recipes
  • Developing understanding of the energetics of food, cooking, and eating
  • Attending cooking classes and group meetings (support persons encouraged)
  • Blood samples for DNA, diet, and visual function analysis
  • Various eye tests to assess current eye health
Participant Benefits

Education and practical skills in healthy cooking, dietary support, and comprehensive eye health assessments.

Eligibility Criteria

Men or women ages 18–80 with stable open‑angle glaucoma. Additional eligibility requirements may be reviewed with the study coordinator.

Additional Information

Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Study Duration
12 months (6 months observation, 6 months active)
Study Compensation
Up to $225
Email
krupp-wellness@health.ucsd.edu
Phone Number
858‑822‑1643

Integrative Prehabilitation Program for Patients Facing Surgery

This study supports patients undergoing gastrointestinal cancer surgery with a comprehensive integrative care plan. The program includes services before and after surgery and is led by UC San Diego experts in mindfulness, dietetics, and exercise physiology.

Study Activities

A treatment development and feasibility study assessing a 3–5 month integrative pre- and post-habilitation program. The program includes mindfulness sessions with a mindfulness coach (MC), dietary counsel visits with a registered dietitian nutritionist (RDN), and physical fitness consultation visits with an exercise physiologist. The study activities consists of mostly virtual visits and surveys, but also includes in-person visits to complete questionnaires and physical evaluations.

Participant Benefits

All services are provided at no cost. Pre- and post-surgical oral nutrition supplements are provided. Participants may experience improved surgical outcomes, reduced anxiety, and enhanced overall well-being.

Eligibility Criteria
  • Adults ages 18–75 undergoing major abdominal surgery for gastrointestinal cancer
  • Must enroll at least 4 weeks—and no more than 3 months—prior to surgery
Additional Information

Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Principal Investigator(s)

Jula Veerapong, MD

Jenn Lee, MD

Study Duration
3-5 months
Email
krupp-wellness@health.ucsd.edu
Phone Number
858-413-7728

Integrative Plant-Based Diet & Behavioral Interventions for Patients with Laryngopharyngeal Reflux

This study explores an Integrative Care Program for reducing symptoms of LPR. Study outcomes will be measured before and after an 8-week intervention including dietary counseling, educational materials, and recipes.

 

Study Activities

The objective of this prospective single center study is to test a whole food, plant-based diet with special attention to certain foods for patients with laryngopharyngeal reflux (LPR).The intervention includes a Principal Investigator–led orientation video and four telehealth visits with a registered dietitian. The study activities also include completing online assessments.

Participant Benefits

Benefits include dietary orientation and expert nutritional counseling, WFPB diet education materials and recipes, and telehealth support for lifestyle and dietary changes.

Eligibility Criteria

Adults aged 18 to 89 years old with 8 weeks or more of laryngeal symptoms (dysphonia/voice hoarseness, throat clearing, sore throat, globus, cough, mucus in throat), that are suspected to have potential LPR and are currently receiving concurrent clinical speech therapy at UC San Diego Health.

Additional Information

Additional study eligibility and participation requirements may be reviewed with the study coordinator. Don't hesitate to get in touch with us for screening.

Principal Investigator(s)
Study Duration
8 weeks
Email
krupp-wellness@health.ucsd.edu
Phone Number
858‑249‑6896

Anti-Inflammatory Rich Diet in First Episode Psychosis

The goal of the study is multi-faceted: to develop and test a dietary intervention based on an anti-inflammatory, whole foods diet pattern using continuous feedback from early psychosis patients and their families, evaluate the feasibility, satisfaction, and adherence of a 5-week diet intervention, and explore whether the intervention effects weight, metabolic parameters, biomarkers, symptoms of psychosis, and overall well-being. The intervention includes individualized dietary counseling, diet education, meal plans, and recipes.

Study analysis in progress.

Principal Investigator(s)

Helen Mirzakhanian, PhD

Kristin Cadenhead, MD, Gordon Saxe MD, PhD 

Email
krupp-wellness@health.ucsd.edu
Phone Number
619-543-7816