Preoperative Flavanols Supplementation in Elderly Patients to Reduce Inflammatory Markers and Improve Mitochondrial Function

Recruiting
Lifestyle Medicine
Natural Products
Experimental

Led by Dr. Byron Fergerson, Clinical Professor and Vice Chair of Anesthesiology at UCSD Health, this study evaluates a flavanol-based supplement aimed at supporting recovery and overall health in patients 50 years or older preparing for hip or knee replacement surgery.

Study Activities

Participants will complete two in-home blood draws, take one 500 mg capsule daily for 14 days, log their intake, and answer questionnaires.

Participant Benefits

While direct health benefits cannot be guaranteed, the flavanol supplement may reduce inflammation and support antioxidant activity. Other possible benefits include improved cognition, mood, and recovery. Participants may receive up to $100 upon completion.

Eligibility Criteria
  • Age 50 or older
  • Reside in San Diego County
  • Scheduled for hip or knee replacement surgery
Additional Information

Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Principal Investigator(s)

Byron Fergerson, MD

Study Duration
2 weeks
Study Compensation
Up to $100
Email
krupp-wellness@health.ucsd.edu
Phone Number
619‑929‑0828
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Evaluating the Effects of Magnesium on Arterial Compliance and Cerebral Blood Flow

Recruiting
Diet & Nutrition
Natural Products
Experimental

This feasibility study aims to examine whether 12 weeks of magnesium supplementation (450 mg magnesium citrate 3x day with food) might increase cerebral blood flow and reduce the stiffness of the medium-sized arteries in the brain of obese patients with metabolic syndrome. Blood and MRI are measured before and after the intervention.

Additional Information

Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Principal Investigator(s)

Thomas Liu, PhD

Ryan Bradley, ND, MPH

Study Duration
12 weeks
Email
krupp-wellness@health.ucsd.edu
Phone Number
858-249-6896
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Anti-Inflammatory Rich Diet in First Episode Psychosis

Recruiting
Diet & Nutrition
Lifestyle Medicine
Experimental

The goal of the study is multi-faceted: develop and test a diet intervention based on anti-inflammatory, wholesome foods using continuous feedback from early psychosis patients and their families; evaluate the feasibility, satisfaction, and adherence of a 5-week diet intervention in 12 patients with early psychosis and explore whether a 5-week adherence to an anti-inflammatory wholesome foods diet effects weight, metabolic parameters, biomarkers, symptoms of psychosis, and overall well-being.

Additional Information

Additional eligibility requirements may be reviewed with the study coordinator, please contact us for screening.

Principal Investigator(s)

Helen Mirzakhanian, PhD

Kristin Cadenhead, MD, Gordon Saxe MD, PhD 

Email
krupp-wellness@health.ucsd.edu
Phone Number
619-543-7816
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