The Effect of Anti-Inflammatory Diet on Clinical and Biologic Outcomes in Long-COVID (PASC) Patients
This study aims to assess the feasibility of a 12-week anti-inflammatory diet (ITIS) among Long-COVID (PASC) patients. This study also explores diet-induced changes in clinical symptoms and plasma inflammatory marker levels. The intervention includes individualized dietary counseling and 2 weeks of a Long-COVID ITIS diet plan including a food basket of key ingredients, recipes, and manuals to learn how to follow an anti-inflammatory diet.
Study analysis in progress.
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Glutathione Support for Health: A Randomized Trial
This randomized, placebo-controlled study aimed to determine the feasibility and potential effects on glutathione status using a Whole-Food Plant-Based (WFPB) diet among an adult population with type-2 diabetes. The intervention group included educational classes and meal-planning recommendations aiming to increase the intake of glutathione-rich foods.
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Clinical and Biological Changes in Rheumatoid Arthritis Patients Exposed to an Anti-inflammatory Diet
This pilot study investigated how a short-term anti-inflammatory diet might reduce pain and inflammation in individuals with rheumatoid arthritis (RA). Over a two-week period, participants followed a diet rich in omega-3 fats, antioxidants, and anti-inflammatory ingredients like turmeric, while avoiding pro-inflammatory foods such as red meat, gluten, and lactose. Researchers observed improvements in joint tenderness, swelling, and overall disease activity, suggesting dietary changes may complement standard RA treatments.
Read the published abstract on the 2019 ACR/ARP Annual Meeting site.
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Clinical, Inflammatory, and Microbiome Effects of Dietary Modification in Women With Endometriosis
This study aimed to determine whether increasing consumption of a Whole-Food Plant-Based (WFPB) diet can improve gut microbiome diversity, quality of life, pain, and inflammation in women with endometriosis. Study outcomes were measured before and after a 3-month intervention, including dietary counseling, online cooking classes, and individual and group health coach sessions.
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Plant-Based Dietary Intervention for Chronic Lymphocytic Leukemia (CLL) Patients
This study aims to determine the feasibility of a whole food, plant-based (WFPB) dietary intervention in low-risk patients with Chronic Lymphocytic Leukemia (CLL). Secondary outcomes explored whether adherence to a WFPB diet was associated with changes in CLL biomarkers and biomarkers and anthropometric measures of cardiometabolic health. The intervention included 8 live cooking classes, and multiple individual sessions with both a dietitian and health coach.
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RCT of a Nutritional Intervention for Endometriosis
This study aims to determine whether increasing consumption of a Whole-Food Plant-Based (WFPB) diet is effective at improving quality of life and pain, and decreasing inflammation in women with endometriosis. Study outcomes will be measured before and after a 3-month intervention, which includes dietary counseling, education materials, recorded cooking classes, and health coaching sessions.
Study Activities
The purpose of this randomized controlled study is to investigate the effectiveness of a 3-month dietary intervention on the quality of life, pain, and inflammation in women with endometriosis. The intervention includes learning and adapting to the Whole Food Plant-Based diet. The diet consists of key plant foods and eliminates animal-based products and processed foods. The study activities also include three visits to complete questionnaires aimed at addressing the study's clinical objectives and to provide blood samples for inflammatory biomarker analysis.
Participant Benefits
Dietary orientation and expert nutrition counseling; WFPB diet education materials and resources; food basket, recipes, and manuals to learn and practice healthy eating.
Eligibility Criteria
Women between 18-45 years old with a diagnosis of Endometriosis who are in stable health condition and medications for the past 3 months
Additional Information
Additional study eligibility and participation requirements may be reviewed with the study coordinator. Don't hesitate to get in touch with us for screening.
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Osteopathic Manipulative Treatment in Newborns with Breastfeeding Difficulties
This randomized, placebo-controlled study aims to determine improvements in breastfeeding difficulty of hospitalized newborns. The control group receives doctor-distributed standard educational handouts regarding breastfeeding. The intervention group receives a 30-minute Osteopathic manipulative treatment (OMT) session, provided daily until discharge.
This study is in development, and recruitment has not yet begun. Once approved, additional information about study goals, eligibility, and participation requirements will be shared here. In the meantime, you may contact the study team using the email address on this page for more information.
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Time-Restricted and Healthy Eating in Hepatocellular Carcinoma
A feasibility and safety study of a time-restricted, healthy eating intervention in patients undergoing liver-directed therapies for Hepatocellular carcinoma (HCC). This twelve-month intervention will focus on prolonged nightly fasting combined with a healthy diet. Successful completion of this feasibility study will provide preliminary data for a larger, appropriately powered, trial to examine effects on HCC clinical outcomes.
Study Activities
Participants will receive nutritional counseling and health coaching on nightly fasting and healthy eating habits throughout the 12-month study. The interventions includes wearing a continuous glucose monitor and an accelerometer for a total of two weeks, meeting virtually with a dietitian four times, attending four clinic visits in La Jolla, and completing assessments and questionnaires. Participants will also track their eating times daily in the Guava health tracker app.
Participant Benefits
While direct health benefits cannot be guaranteed, prolonged nightly fasting could improve sleep, stabilize blood sugar, reduce inflammation, and enhance metabolic health. Benefits include dietary orientation, expert dietary counseling, education materials, recipes, and access to the Guava health management app. Eligible participants who complete all study visits and requirements may receive up to $200 in compensation.
Eligibility Criteria
Participants must be 18 years or older, have a BMI greater than 27 kg/m², currently practice nightly fasting of less than 12 hours, and be diagnosed with early or mid-stage liver cancer referred for liver-directed therapy.
Additional Information
Additional study eligibility and participation requirements may be reviewed with the study coordinator. Don't hesitate to get in touch with us for screening.
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