A randomized, double-blinded, placebo-controlled clinical trial to evaluate the safety of FoTv (a combination of two polypore mushrooms, Fomitopsis officinalis, and Trametes versicolor) in an adult population at the time of COVID-19 vaccination. Researchers examined the effect of FoTv vs. placebo for use as an adjunct to vaccination for COVID-19. Vaccine-related side effects following COVID-19 vaccination were examined in both study groups.
A multi-centered, randomized, double-blinded, placebo-controlled clinical trial to evaluate the safety of FoTv (a combination of two polypore mushrooms, Fomitopsis officinalis and Trametes versicolor) for COVID-positive outpatients with mild-to-moderate symptoms. Researchers used changes in COVID-19 viral load, blood markers, and a 14-day symptom diary to examine the safety, feasibility, and preliminary effects of the study product versus placebo.
A feasibility and safety study of a time-restricted, healthy eating intervention in patients undergoing liver-directed therapies for Hepatocellular carcinoma (HCC). This twelve-month intervention will focus on prolonged nightly fasting combined with a healthy diet. Successful completion of this feasibility study will provide preliminary data for a larger, appropriately powered, trial to examine effects on HCC clinical outcomes.
Participants will receive nutritional counseling and health coaching on nightly fasting and healthy eating habits throughout the 12-month study. The interventions includes wearing a continuous glucose monitor and an accelerometer for a total of two weeks, meeting virtually with a dietitian four times, attending four clinic visits in La Jolla, and completing assessments and questionnaires. Participants will also track their eating times daily in the Guava health tracker app.
While direct health benefits cannot be guaranteed, prolonged nightly fasting could improve sleep, stabilize blood sugar, reduce inflammation, and enhance metabolic health. Benefits include dietary orientation, expert dietary counseling, education materials, recipes, and access to the Guava health management app. Eligible participants who complete all study visits and requirements may receive up to $200 in compensation.
Participants must be 18 years or older, have a BMI greater than 27 kg/m², currently practice nightly fasting of less than 12 hours, and be diagnosed with early or mid-stage liver cancer referred for liver-directed therapy.
Additional study eligibility and participation requirements may be reviewed with the study coordinator. Don't hesitate to get in touch with us for screening.
