Krupp Center for Integrative Research

PBR Resources

The National Institutes of Health (NIH) is emphasizing the importance of Practice-Based Research (PBR) as a practical and real-world approach to advancing clinical research.  Few physicians have training in the importance of and how to implement PBR. We host periodic one-day CME workshops to inform clinical faculty how to conduct PBR within their clinics to advance this important clinical research initiative.

The Value of PBR                    

  • Sets new standards for integrative health through validated methods
  • Advances integrative medicine in preventing and treating chronic disease
  • Highlights the role of natural therapies in both acute and chronic care
  • Expands awareness and access to integrative care across healthcare

PBR Course Learning Objectives

  • Enhance motivation and ability of clinical faculty to direct and conduct funded Practice-Based Research
  • Identify resources, structures, and processes needed to support faculty in conducting PBR
  • Create actionable ideas for multiple PBR projects that engage clinical teams

Practice-Based Research (PBR) and Pragmatic Studies Workshop Materials

PBR Worksheet

Fill out this worksheet to help us understand your PBR needs.

Practical issues in implementing PBR

Wilson Pace, MD, University of Colorado, Denver

Discusses the advances of Integrative Medicine research and how it is influencing the direction of allopathic practice.

Integrative Medicine PBR; BRAVENET and PRIMIER

Jeffery A. Dusek, PhD, Integrative Health Research Center, Penny George Institute for Health and Healing

Discusses the advances of Integrative Medicine research and how it is influencing the direction of allopathic practice.

Overview of PBR Efforts at UC San Diego

Rusty Kallenberg, MD, & William Sieber, PhD, UC San Diego

Learn about opportunities at UC San Diego, and how to move your practice forward with PBR.

Resources and Pilot Grants to Support PBR

Paul J. Mills, PhD, UC San Diego

Discover resources and funding to support your PBR ideas.

Research designs appropriate for PBR

Shahrokh Golshan, PhD, UC San Diego

Presents and discusses different design and statistical issues involved in common and practical PBR trial designs and how to collaborate with a statistician.

Qualitative Assessments

Samantha Hurst, PhD, UC San Diego

Informs attendees about the use of qualitative data in developing contextualized evaluation/research efforts in their practices, including bridging qualitative data with quantitative data in mixed methods designs.

Identifying proper and practical endpoints; The Promise of PROMIS

Rusty Kallenberg, MD, UC San Diego

Discusses the NIH PROMIS questionnaire system and how to use it for PBR.

Core Services

Researchers in integrative health face distinct challenges in designing, managing, and translating their work into meaningful outcomes. In order to aid researchers, and in order to reduce the cost and improve efficiency of our grants, the Krupp Center for Integrative Health accelerates this process by offering expert guidance, operational support, and specialized tools across every stage of research through a coordinated suite of core services. To learn more or inquire about support for your project, contact us.

Study Design & Regulatory Support

We help researchers build a strong foundation for their work through research design and statistical consultation, support with IRB application development and other regulatory correspondence, and guidance on selecting appropriate questionnaires and assessments. Our team ensures your study is methodologically sound and ethically aligned from the start.

Research design and statistical consultation

Project/study management

Regulatory correspondence support

Grant application development

IRB application development

Questionnaire / assessments selection

Grant & Project Development

From idea to implementation, we offer expert assistance with grant application development, comprehensive project and study management, and manuscript preparation to support successful funding, execution, and dissemination. Whether you're launching a new study or preparing results for publication, we’re here to help every step of the way.

Database development

Data collection and management

Manuscript preparation

Clinical research coordination support

Clinical & Integrative Support

Enhancing both participant care and study design, our services include consultation in complementary and integrative medicine, dietary counseling, and wellness coaching. These offerings provide added depth to research protocols while supporting overall health outcomes.

CAM/IM modalities consultation

Health and Wellness coaching

Dietary counseling and intervention

Apply for a Grant

KCIR members are eligible to apply for a Krupp Award; if this is your first time applying for an award, ensure you have completed a membership application. Before diving into the award application process, please review the Request for Applications (RFA) document below. In order to plan for your online submission, we offer the invitation to review potential project ideas that may be developed. We will advise applicants on potential relevance of concept ideas as they relate to the objectives of the Krupp Endowed Fund (KEF). Submitting a concept idea for review is not necessary. After an idea is well-developed, application for an award begins with a Letter of Intent (LOI).

Step 1

Review the RFA

Read this essential in-depth document will provide all the necessary information about applying for a Krupp Award, from eligibility and expected timelines to format specifications of submissions.

Step 2

KCIR Membership

Membership is required for applicants seeking funding from the Krupp Endowment Fund. Submit a membership application first, then proceed to the next step.

 

Step 3

Concept Idea Form

Ensure the concept idea is relevant to the aim and objective of the Krupp Center for Integrative Research by submitting a concept idea for review. Our team will provide early feedback, which is key to ensuring efficiency and developing a stronger application.

Step 4

Submit LOI

Submit a Letter of Intent (LOI). Outline the research question, target population, methods, and how your work advances integrative health. LOIs are evaluated based on eligibility, scientific merit, cost efficiency.

Step 5

Grant Application

Upon review and approval of the Concept Idea and LOI, a grant application will be sent directly to the Principal Investigator for completion.

Step 6

Fund Awarded

If grant application is approved, KCIR staff will coordinate with the awardee(s) to ensure funding is distributed to the research project.